• De esta forma siguiendo la multicitada met fora

  2019-05-07

  

  De esta forma, siguiendo la multicitada metáfora de Hemingway, el relato policiaco es solamente la punta del iceberg, mientras que los excesos de la política se encuentran debajo del mar (de lama). El relato policíaco, entonces, no es sólo un “pretexto narrativo”, o una simple guía para el lector me

• More than structural haemoglobin variants

  2019-05-07

  

  More than 900 structural haemoglobin variants have been described. Of these more than 100 show high oxygen affinity [2]. Erythrocytosis caused by Hb Ypsilanti was first described in 1967 [3], and the mutation results in substitution of amino buy diazoxide (β99 Asp→Tyr) involved in the stability of t

• br AML therapies with curative intent br Alternative treatme

  2019-05-07

  

  AML therapies with curative intent Alternative treatment strategies Targeted therapies: the new kids on the block The recognition of specific mutations as genetic drivers or facilitators of AML has led to the development of new inhibitors and targeted treatment options. New promising drug c

• Regarding the pathophysiology of HF

  2019-05-07

  

  Regarding the pathophysiology of HF with preserved LVEF, AF is one of the most important precipitating factors related to diastolic dysfunction [22,23]. AF might have important roles in the pathogenesis of HF with preserved EF in association with diastolic HF. Compared with JCARE-CARD, which include

• br Planteamientos Previos El presente estudio muestra

  2019-05-06

  

  Planteamientos Previos El presente estudio muestra la estrecha relación entre los procesos identitarios y las transformaciones de los contextos migratorios. Centrándose en el caso de los migrantes indígenas de Otavalo (Ecuador) en una de las ciudades del sur de España, la investigación parte de u

• nicergoline Romiplostim is an Fc fusion protein

  2019-05-06

  

  Romiplostim is an Fc-fusion protein that augments thrombopoiesis by binding to and activating the thrombopoietin receptor. It is approved for the treatment of thrombocytopenia in patients with chronic immune thrombocytopenic purpura who have had an insufficient response to corticosteroids, immunoglo

• Interpretation AMWHO is a useful forum for

  2019-05-06

  

  Interpretation AMWHO is a useful forum for students to improve their knowledge of global health issues, and sharpen their skills in diplomacy, communication, problem solving, and conflict resolution. Emory University (Atlanta, GA, USA) will host the next national AMWHO conference in October, 2016. E

• Introduction This document does not address the

  2019-05-06

  

  Introduction This document does not address the indications of genetic testing in patients affected by inherited arrhythmias and their family members. Diagnostic, prognostic, and therapeutic implications of the results of genetic testing also are not included in this document because this topic has

• In the management of BrS patients

  2019-05-06

  

  In the management of BrS patients, it is important to avoid or treat certain drugs or circumstances such as a febrile state, electrolyte disturbances (hyperkalemia and hypercalcemia), and the use of class Ia/Ic antiarrhythmic drugs, vagotonic agents, beta-adrenergic antagonists, tricyclic antidepres

• br Case report His physical examination and basic laboratory

  2019-05-06

  

  Case report His physical examination and basic laboratory data were normal. No organic heart disease other than dextrocardia was detected on electrocardiography, chest radiography, and echocardiography (Fig. 1). A head-up tilt test (HUT) was performed according to the ESC/ACC guidelines [7,8]. T

• o6 methylguanine methyltransferase br Discussion This study

  2019-05-06

  

  Discussion This study shows that the risk of all-cause mortality in patients with atrial fibrillation is directly associated with RDW in a dose-response manner. This association was independent of known risk factors of mortality. Notably, RDW is associated with all-cause mortality regardless of a

• A number of clinical studies have confirmed

  2019-05-06

  

  A number of clinical studies have confirmed the beneficial effect of ranolazine in either prevention or treatment of AF. The first strong evidence was provided by MERLIN-TIMI 36 trial [the Metabolic Efficiency With Ranolazine for Less Ischemia in Non–ST-Elevation Acute Coronary Syndrome–Thrombolysis

• br Las fuerzas Impulsoras de

  2019-05-06

  

  Las fuerzas Impulsoras de la Internacionalización de la ciencia y la technología en América latina Los eLementos indicativos de la internacionalizacion de la ciencia y la tecnología en América Latina Debates ytensiones en torno de la internacionalización de la ciencia y la technología en Amé

• Para garantizar la aplicaci n y permanencia

  2019-05-05

  

  Para garantizar la aplicación y permanencia de las reformas emprendidas, se necesitaba de un marco normativo institucional que brindara estabilidad al modelo, emitiendo señales de confianza al capital transnacional y otros actores privados que invertían en Perú. La Constitución de 1993, elaborada po

• citco Evidence of a variant induction of apoptosis to vorino

  2019-05-05

  

  Evidence of a variant induction of apoptosis to vorinostat in different DLBCL cell lines according to HAT mutational status implies that defects in CREBBP/EP300 could potentially explain the heterogeneous observations in clinical trials of vorinostat in NHL. These findings, however, need to be confi

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