• br Role of the funding source br Contributions

  2019-05-28

  

  Role of the funding source Contributions Conflicts of interest Acknowledgments The authors would like to thank the patients who participated in this study and their families. The authors would also like to acknowledge the writing assistance of Stephen Mosley, Ph.D., of Knowledge Point 36

• br Environmental pollution is a global problem and the

  2019-05-28

  

  Environmental pollution is a global problem and the subject of increasing worldwide public health concern. In particular, air pollution is regarded as the largest single environmental risk to health. More than 80% of people living in urban areas that monitor air pollution are exposed to air qualit

• br In its July editorial drew attention to

  2019-05-28

  

  In its July editorial, drew attention to the ethical challenges posed by the Zika caspofungin outbreak. The Regional Program on Bioethics at the Pan American Health Organization (PAHO) arranged an ethics consultation, funded by the Wellcome Trust, to provide ethically sound guidance for the outbre

• Bacterial LPS stimulates monocytes and

  2019-05-28

  

  Bacterial LPS stimulates monocytes and tissue macrophages to release TNF-α and IL-1, which then stimulate secondary response cytokines, including IL-6. In addition to hematopoietic cells, IL-6 is synthesized by many different types of nonhematopoietic cells, including endothelium, lasting for an ext

• After exclusion of secondary causes of

  2019-05-28

  

  After exclusion of secondary causes of eosinophilia, diagnostic evaluation of primary eosinophilias relies on a combination of morphologic review of the blood and marrow, standard cytogenetics, fluorescent in situ hybridization, flow immunocytometry, and T-cell clonality assessment to detect histopa

• Recently denosumab demonstrated a significant delay in the o

  2019-05-28

  

  Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R

• As shown in Fig out

  2019-05-28

  

  As shown in Fig. 2, 40 out of the 60 patients (66.6%) who developed amiodarone-induced hypothyroidism, and 10 out of the 30 patients (33.3%) who developed amiodarone-induced hyperthyroidism, were diagnosed within two years of endothelin receptor antagonists of amiodarone therapy. Amiodarone-induced

• br A KCNJ mutation corresponding to an S L

  2019-05-27

  

  A KCNJ8 mutation, corresponding to an S422L mutation in the protein, was first identified in a 14-year-old girl with early repolarization [59], who suffered frequent VF attacks. KCNJ8 encodes Kir6.1, which has 2 transmembrane regions, and the KATP channel is composed of a complex of Kir6.1 or Kir

• br Discussion The mechanism of

  2019-05-27

  

  Discussion The mechanism of verapamil-sensitive ILVT has been suggested as re-entry with an excitable gap and a slow conduction, because the VT can be induced, entrained, and terminated by programmed ventricular or atrial stimulation [1–6]. In addition, previous studies have suggested that the re

• CT analysis of tumour bearing bones

  2019-05-27

  

  μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic the most successful film caused sustained bone effects thr

• Era tal el recelo que hab a sobre el

  2019-05-27

  

  Era tal el recelo que había sobre el enriquecimiento de los ministros que en enero de 1622 se intentó investigar los orígenes de su riqueza. El mismo mes se publicó un decreto que estipulaba que todos los que habían tenido cargos p2y inhibitor partir de 1592 debían inventariar sus propiedades ante u

• Estimates of life expectancy are

  2019-05-27

  

  Estimates of life expectancy are of obvious importance to people with HIV-1, and are essential to monitor and predict the progress of the HIV/AIDS epidemic and to plan health services. The Rwandan study reported by Sabin Nsanzimana and colleagues in is the first from sub-Saharan Africa to focus on t

• bcrp transporter Expresi n de la complejidad de

  2019-05-27

  

  Expresión de la complejidad de esta articulación de los movimientos de la región en este proyecto es, además, la gestación —de forma paralela bcrp transporter los cms, desde 2009— de la Articulación Continental de Movimientos Sociales hacia el alba, cuyo punto de partida es la “Carta de los Movimien

• br Efforts to address malnutrition maternal and child mortal

  2019-05-27

  

  Efforts to address malnutrition, maternal and child mortality, and other global health priorities are heavily reliant on behaviour change, including adoption and correct use of health technology, and following treatment recommendations. One long-standing concern is the limited effectiveness of man

• The communities on both sides of

  2019-05-27

  

  The communities on both sides of the South Sudan–Uganda border share the risk of sleeping sickness, as transmission of still occurs in this oxyntomodulin region. Most of the South Sudanese refugees come from endemic areas and have been accommodated in multiple camps in Adjumani and Yumbe districts

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