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br Role of DDR receptor in the development of Bone
2020-07-28

Role of DDR2 receptor in the development of Bone in human DDR2 receptor and MMP-13 expression Type II collagen protein in articular cartilage is highly stable structure as its half-life is 117 years [43]. The chondrocytes have limited ability to synthesis type II collagen protein in the matrix
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To the best of our knowledge this is the first
2020-07-28

To the best of our knowledge, this is the first report on the effect of chronic SSRI treatment on the acquisition and TSU-68 of fear-potentiated startle in rodents. The lack of effect on expression of cued fear is in line with the single human fear-potentiated startle study available (Grillon et al
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In this study we have used a mouse model
2020-07-28

In this study we have used a mouse model of post-incisional pain that closely mimics the surgical procedure in humans in order to evaluate the role of CRF/CRF1 receptors in the pro-nociceptive and inflammatory response to injury (incision), using genetically engineered mice lacking functional CRF1 r
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br Disclosure statement br Acknowledgment and sources of
2020-07-28

Disclosure statement Acknowledgment and sources of funding We would like to thank Dr. Brain Lau, who helped us strongly with the editing and reviewing of the manuscript. The research was funded by the Joint Council Office (JCO), Agency for Science, Technology & Research (A*STAR), Singapore.
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Interestingly several studies in fragments of
2020-07-28

Interestingly, several studies in fragments of villous tissue from human placenta, have shown volume-activated amino Butaprost sale efflux via a pathway sensitive to classic inhibitors of anionic transporters (DIDS, NPPB and niflumic acid), consistent with the presence of volume-activated Cl− channe
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Saito et al reported that d
2020-07-27

Saito et al. reported that diabetic bone has lower lysyl oxidase-derived enzymatic cross-links in collagen compared to non-diabetic bone, based on studies performed in a rat model [9]. Lysyl oxidase plays a pivotal role in bone development and function, as revealed in classical studies [10], [11]. L
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Several types of protease inhibitors have been tested as
2020-07-27

Several types of protease inhibitors have been tested as potential agents for plant protection against CPB in the form of dietary additives or transgenic plants, but with varying success [6], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20]. Rice and barley cystatins expressed in potato ca
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br Methods br Results The characteristics of the
2020-07-27

Methods Results The characteristics of the 20 control subjects and 63 patients stratified by SDB severity, matched for age, sex, and BMI z-score, are described in Table 1. As expected, AHI, OAI, ODI, and SLT90% increased and SpO2 decreased progressively with the severity of the disease. Dis
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br Conflict of interest br Acknowledgments The colored figur
2020-07-27

Conflict of interest Acknowledgments The colored figures in this paper were evaluated to ensure that their perception was accurately conveyed to colorblind readers [139]. The author thanks Laura M. Roskoski for providing editorial and bibliographic assistance. I also thank Josie Rudnicki and J
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We have previously shown that vigilin
2020-07-27

We have previously shown that vigilin overexpression can inhibit breast cancer cell invasiveness and motility in vitro [9]. Here, we show that deletion of the 69 nt vigilin binding element obviates effect of ABT with excess CSF-1R mRNA 3′UTR on enhancement of in vitro parameters of breast cancer cel
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Physiological changes induced by CRF are mediated through CR
2020-07-27

Physiological changes induced by CRF are mediated through CRF1 and CRF2 receptors (Chang et al., 1993, Lovenberg et al., 1995). Previous findings with CRF1 receptor antagonists showed that activation of CRF1 receptor is involved in maternal separation-induced ultrasonic vocalizations (Kehne et al.,
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br Introduction We consider normal algebraic
2020-07-27

Introduction We consider normal algebraic varieties X defined over the field of complex numbers. If X has finitely generated divisor class group K and only constant invertible global regular functions, then one defines the K-graded Cox ring of X as follows, see [2] for details: If the Cox ring
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Yet the standards fall back on the development process
2020-07-27

Yet, the standards fall back on the development process with justification. As shown by Littlewood and Strigini (1993), the extent to which the reliability of software (both OTS and bespoke) can be proved by testing is severely limited––not because appropriate tests cannot be devised, but because ad
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The yeast Rad p radiation sensitive
2020-07-26

The yeast Rad6p (radiation sensitive 6, also called Ubc2) E2 ubiquitin-conjugating enzyme is a member of the highly conserved UBC proteins in eukaryotes (Xu et al., 2009). Rad6p is involved in several cellular processes, including DNA repair, transcriptional activation and silencing, histone ubiquit
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We have previously characterized the leucine
2020-07-25

We have previously characterized the leucine-rich NESs located within the zinc-binding domains of mucosal high risk HPV16 E7 (76IRTLEDLLM84) and low risk HPV11 E7 (76IRQLQDLLL84) mediating their nuclear export in a CRM1 dependent manner (Knapp et al., 2009, McKee et al., 2013). The zinc-binding doma
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