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  • Finally we tested whether the B cell differentiation defect

    2018-10-20

    Finally, we tested whether the B cell differentiation defect in the OsxCre;iDTR mutants could be rescued in vivo by intravenous administration of recombinant IL-7 and IGF-1. Both controls and mutants were subjected to daily injections of DT, DT + IL-7, or DT + IGF-1 for 12 days. At the end of the re

  • Remarkably the changes described suggest

    2018-10-20

    Remarkably, the changes described suggest that in vivo reprogramming-induced dedifferentiation renders a change at telomeres toward a more “juvenile” state, which in turn resembles that of ESCs and adult stem purchase GW788388 (see Figure 7). In this regard, we have previously described telomerase-

  • Hello world!

    2018-07-29

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