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In the present study we aimed at integrating single cell
2018-10-30

In the present study we aimed at integrating single cell properties and network activity in dissociated cultures of Ts65Dn and Tc1 mouse models and in their respective diploid cultures. We report here that network activity was reduced and that trisomic neurons were less excitable due to an increase
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br Methods br Results The response rate to
2018-10-30

Methods Results The response rate to the survey was very high (318 out of 345; 92%). Mean age of the participating cardiologists was 49.2±11.4years (range, 27 to 73years); 250 (79%) were men. One hundred seventy three (54%) cardiologists were working in private practice and the others (145; 46
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SEA0400 br Author contributions br Conflict of interest br
2018-10-30

Author contributions Conflict of interest Acknowledgments Introduction The use of fully suppressive combination Anti-Retroviral Therapy (c-ART), aside from efficiently inhibiting viral replication, has provided important insights into the characteristics and dynamics of the persistent la
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At the cellular level ED is thought to be
2018-10-30

At the cellular level, ED is thought to be caused by neuro-vascular or hormonal dysfunction resulting in impaired vasodilatation of penile folate analogue (Salonia et al., 2012; Weyne and Albersen, 2014). When the natural nocturnal erection is lost, the penis tissue enters a chronic hypoxic state l
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One of the limitations of this study is
2018-10-29

One of the limitations of this study is the differences in the patient populations between the two CRC patient cohorts. As shown in Table 1 and 2, there were differences in the number of patients with stage IV CRC between cohort 1 and cohort 2. At first, we validated the clinical significance of SNO
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br Experimental design materials and methods br Conflict of
2018-10-29

Experimental design, materials and methods Conflict of Interest The authors (KMK, JRR, MAB, KMR) of this pyk2 inhibitor manuscript (Functional magnetic resonance imaging data of incremental increases in visuo-spatial difficulty in an adult lifespan sample) have no conflicts of interest to rep
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The data presented in Figs describe the
2018-10-29

The data presented in Figs. 1–9 describe the standardization of enzyme and analytes. Reaction progress curve data is provided for experiments evaluating the effects of variable substrate concentration (Figs. 10–13, [Myr] = 8.83Uml−1), variable enzyme concentration (Fig. 14), variable rolipram (Figs
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br Acknowledgements We would like
2018-10-29

Acknowledgements We would like to recognize the National Science Foundation Grant CMMI-0954580 for funding this research. Introduction The Indian government has expressed an aim to provide clean drinking water to all of its citizens (Government of India, 2002), but this target has yet to be a
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br Experimental work br Results The samples were friction
2018-10-29

Experimental work Results The samples were friction welded. It can be seen from Fig. 6 that the heating time, upset time and interlayer thickness are the major criteria for joint performance. When the weld interfaces of Sample 13 were analyzed after experimentation, the friction and upset time
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Extensive work on the influence of
2018-10-29

Extensive work on the influence of pin geometry on mechanical properties of 2014 aluminium alloy friction stir welds has been carried out by Zhao et al. [18]. Taper screw thread pin weld was reported to have the highest weld joint efficiency (75%) compared to the threaded cylindrical tool pin profil
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The lateral window sinus lift is the
2018-10-29

The lateral window sinus lift is the traditional treatment option of choice prior to implant placement when polylactic-co-glycolic parp inhibitor (PLGA) and Poloxamer 407 [11]. The present study compared the implant stability and marginal bone levels of dental implants immediately placed into graf
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Therefore the main actions to be undertaken
2018-10-29

Therefore, the main actions to be undertaken are as follows: The organization of the garden, which is said to be in line with the old Turkish castle tradition, must be canceled. The elements irrelevant to the history of castle must immediately be removed. The mosque of the castle must be restored. T
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The rest of this paper
2018-10-29

The rest of this keap1-nrf2 pathway paper is structured as follows. First, Section 2 focuses on HSR network planning at the national level. Three HSR sub-categories are investigated, namely, the national HSR trunk network, the national HSR extensional network, and the intercity HSR network. Section
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Only month after the last surgery the patient experienced
2018-10-29

Only 1 month after the last surgery, the patient experienced diplopia with blurred vision, which was accompanied by dizziness, headache, and poor appetite. MRI of the gli1 showed some leptomeningeal enhancement around the brain stem and suspicion of seeding (Fig. 3A and B). Spinal MRI showed that l
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br Minimally invasive coronary revascularization The minimal
2018-10-29

Minimally invasive coronary revascularization The minimally invasive direct coronary artery bypass (MIDCAB) procedure was introduced into the surgical literature in 1995. The MIDCAB was usually performed through anterolateral thoracotomy, harvesting the left internal mammary artery and constructi
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