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br Results and Discussion In order to
2018-10-22
Results and Discussion In order to identify regulators of ISC behavior, we carried out a screen using esgGal4 in the posterior midgut. From this screen, Dbr was identified as a candidate. Single esg+ cells are interspersed in young flies (Figure 1A). In aged flies, esg+ cells are clustered, enlar
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KN-93 br Conflict of interest statement The following are th
2018-10-22
Conflict of interest statement The following are the supplementary data related to this article. Acknowledgments This research was supported by funds to R.C. and F.C. from the Italian Ministry of Education, University and Research (MIUR). Introduction Besides hematopoietic stem KN-93 (HS
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Due to the limited proliferative capability of CMs large
2018-10-20
Due to the limited proliferative capability of CMs, large scale production of CMs is based on the expansion of pluripotent hESC followed by a CM differentiation step (Chen et al., 2014). Scaling up of hESC expansion in monolayer (MNL) culture platform is problematic mainly due to surface area limita
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br Materials and methods br Results br
2018-10-20
Materials and methods Results Discussion Human olfactory stem cells can be grown in neurospheres (Reynolds and Weiss, 1992). Murrell et al. obtained human mucosa by biopsy and generated OSs. They separated olfactory mucosa into lamina propria and epithelium. After separately dissociated, ce
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br Material and methods br Results br Discussion In our
2018-10-20
Material and methods Results Discussion In our previous studies, we showed that SVCT2 plays an important role in BMSC differentiation, cell attachment, and migration (Fulzele et al, 2013; Sangani et al, 2014). We also demonstrated that the SVCT2 transporter is down-regulated by oxidative st
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br Conclusions br Acknowledgements br Background Much of the
2018-10-20
Conclusions: Acknowledgements Background Much of the recent attention paid to human bone marrow stromal mol to ml (hBMSCs) is a consequence of their promise in cell-based therapy (Yi and Song, 2012). Features of BMSCs claimed that beneficial may include the capacity to home to sites of dam
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DNA fingerprinting confirmed the genetic relation
2018-10-20
DNA fingerprinting confirmed the genetic relation of the derivative line to the parental somatic line (Fig. 1B). The latrunculin manufacturer exhibited normal karyotype (46, XY) upon G-band analysis (Fig. 1C). Pluripotency was verified by gene expression of pluripotent stem cell markers Oct4, Sox2
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We recently reported that iPSCs can
2018-10-20
We recently reported that iPSCs can be generated using non-modified mRNA (Arnold et al., 2012). In this report we will focus on the crucial steps for successfully applying this method. Material and methods Results Discussion Acknowledgments The work was supported by funding from the Ger
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CBP is implicated in different biological functions
2018-10-20
CBP is implicated in different biological functions with an essential role in maintaining normal germ cells development. CBP is expressed in primordial germ cells (PGCs) and in ESCs but is highly expressed in PGCs compared with ESCs. Proper levels of CBP have been shown to be important for hematopoi
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Dental pulp stem cells DPSCs also known as dental
2018-10-20
Dental pulp stem EZ Cap Reagent GG Supplier (DPSCs), also known as dental pulp-derived mesenchymal stem cells, are a multipotent adult stem cell population that has a high proliferative potential. DPSCs in this study isolated from adult teeth are easily accessible and cryopreservable for long perio
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Muscle resident Sca CD cells
2018-10-20
Muscle-resident Sca-1+CD45− flunixin meglumine were minimally responsive to HFD and/or endurance exercise. A significant reduction in VEGF gene expression was observed in MDSCs in response to HFD, yet no other changes were noted in MDSC relative quantity or the expression of genes related to ECM re
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br Introduction A key question
2018-10-20
Introduction A key question in cardiovascular biology is to what degree the heart is able to regenerate after tissue damage from either cardiac stem cells or cardiomyocyte division. Cardiovascular disease including myocardial infarct is currently one of the leading causes of death worldwide, and
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br Introduction Mammary gland development is controlled
2018-10-20
Introduction Mammary gland development is controlled by the endocrine system, in particular by the ovarian steroid hormones, estrogen and progesterone, and by the pituitary hormones, growth hormone (GH) and prolactin. Studies in animal models showed that GH deficiency impairs mammary gland develo
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In D the generation of confluent monolayers ahead
2018-10-20
In 2D, the generation of confluent monolayers ahead of differentiation was noted to be critical for efficient cardiomyogenesis (Lian et al., 2013). This suggests that the cell density, which impacts on cell-cell contacts and the concentration of paracrine factors, plays a role. Lian et al. (2013) th
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Introduction Cumulative lifetime hormone exposure as a resul
2018-10-20
Introduction Cumulative lifetime hormone exposure as a result of natural menstrual cycles and exogenous hormone therapies is a strong determinant of increased breast cancer risk. Progesterone, an ovarian steroid hormone that peaks during the luteal phase of the menstrual cycle, promotes the expansi
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