• The inhibitory preference of B eurycoma and D microcarpum ex

  2018-11-06

  

  The inhibitory preference of B. eurycoma and D. microcarpum extracts for α-glucosidase over α-amylase observed in this study is of interest as it may give the extracts pharmacological advantage over acarbose, a widely used synthetic oral hypoglycemic drug. Acarbose inhibits both α-amylase and α-gluc

• br Materials and methods br

  2018-11-06

  

  Materials and methods Results and discussion Conclusion India has enormous varieties of underutilized fruits that vary in appearance and organoleptic features as well as presence of varieties of bioactive compounds. The delicious sweet fruits as well as the seeds of M. hexandra (Roxb.) Duba

• Beside its efficacy in the treatment of refractory

  2018-11-06

  

  Beside its efficacy in the treatment of refractory epilepsy, the ketogenic diet has been suggested to be useful in the therapy of neurodegenerative and neuromuscular diseases including AD, Parkinson’s disease, amyotrophic lateral sclerosis and mitochondrial disorders [34]. The ketogenic diet is like

• One BRCA BRCA delT and

  2018-11-06

  

  One BRCA2 (BRCA2 6174 delT) and two BRCA1 (BRCA1 5382insC and BRCA1 185 delAG) founder mutations account for 90% of inherited BRCA1/2 mutations in patients of Ashkenazi Jewish descent (Petrucelli et al., 2010). Because 0.1% of the Ashkenazi population carries the BRCA1 5382insC mutation, we estimate

• The following are the supplementary data related to this

  2018-11-06

  

  The following are the supplementary data related to this article. Acknowledgments The authors thank the staff of the Cell Processing Laboratory, Department of Transfusion Medicine, Clinical Center, NIH for their support of these studies. We also thank Dr. Francesco Marincola and Dr. Ena Wang (De

• br Methods br Results br Discussion The results

  2018-11-06

  

  Methods Results Discussion The results demonstrate that O2 partial pressure influences SPCs mobilization with repetitive treatments. Whether this is due to augmented NOS-3 activation requires additional study. SPCs mobilization in response to a variety of drugs is compromised by older age,

• The following are the supplementary related to this article

  2018-11-06

  

  The following are the supplementary related to this article. Acknowledgment We would like to thank for the financial support by the ALF Research Grant, Stockholm County Council; Chinese Scholarship Council, PR China; Craig Hospital Foundation, CO, USA; Magnus Bergvall Foundation, Svenska Läkarsä

• Defining regeneration as the replacement of

  2018-11-06

  

  Defining regeneration as “the replacement of missing structures following injury” (Morgan, 1901), compensatory lung growth after pneumonectomy is an extraordinary example of mammalian tissue regeneration. After left pneumonectomy, the missing lung tissue is not regrown orthotopically in the left hil

• In Part I of this paper I will introduce

  2018-11-06

  

  In Part I of this paper I will introduce four central challenges to the organization of international stem cell trials that emerge from this high level of regulatory variation. These obstacles apply in principle to all innovative multi-country stem cell trials that are subject to approval by a drug

• Introduction The mechanisms by which pluripotency

  2018-11-06

  

  Introduction The mechanisms by which pluripotency regulators dictate self-renewal versus differentiation are only recently being studied (Wagner et al., 2010; Niwa et al., 2009). In addition, various approaches are being developed to examine such processes (Wang et al, 2013). The transcriptional re

• While we showed that endothelial cells

  2018-11-06

  

  While we showed that endothelial Erlotinib Hydrochloride manufacturer and astrocytes contribute to the regulation in the neurogenic niche of the hippocampus, the role of pericytes is far less conclusive. For most time pericytes have received relatively little attention and only more recently their

• To confirm the pluripotency of the MIXL eGFP

  2018-11-06

  

  To confirm the pluripotency of the MIXL1-eGFP hESCs, the expression of several pluripotency markers was analyzed by quantitative real-time PCR as well as immunocytochemsitry. Endogenous expression of NANOG, OCT4 and SOX2 was determined at the mRNA level by real-time PCR (Fig. 1C). Protein expression

• butein br Conflict of interest br

  2018-11-06

  

  Conflict of interest Acknowledgements Funding is provided by NSF-CMMI 1537745 and Northeast Ohio Medical University to L.N.C. We thank Drs. Mark Stewart (SUNY Downstate) and Ellen Covey (University of Washington) for donating bats to seed the colonies used in this study. Introduction The e

• In addition to the lack of a

  2018-11-06

  

  In addition to the lack of a control group, our study has other recognizable limitations. As stated above, this study lacks a fixed/standardized cell dose, making it difficult to establish a real and efficacious cell dosage regime. Characterization of the cellular composition of the resulting SVF in

• Main Text We appreciate the interest that

  2018-11-06

  

  Main Text We appreciate the interest that Andersen et al. (2014) have shown in our work on neonatal cardiac regeneration. Their recent paper relates directly to resection methodology first presented by Porrello et al. (2011) and describes a failure to reproduce the observations made in that study r

15780 records 1036/1052 page Previous Next First page 上5页 10361037103810391040 下5页 Last page