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Concomitant with its suppressive effect
2018-11-12
Concomitant with its suppressive effect on blast colony formation, the inclusion of WNT3A, or the WNT agonist BIO, in methylcellulose cultures promoted the emergence of colonies we termed “mesospheres” (Figure 7H). These colonies were capable of osteogenic, adipogenic, and smooth muscle differentiat
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Due to the limited numbers of PGCs
2018-11-12
Due to the limited numbers of PGCs in mouse embryos, it is difficult to dissect the molecular mechanisms of early germ cell development. Recently, using ESC in vitro differentiation models, a number of studies demonstrated that Dazl, Blimp1, Lin28, and possibly Rhox6/Psx1, participated in PGC format
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We next aimed to test the differentiation capabilities of
2018-11-12
We next aimed to test the differentiation capabilities of the EZ spheres. We found that at any passage for all cell lines regardless of cryopreservation, EZ spheres can be placed in specific neural induction media for terminal neuronal or glial cell differentiation using protocols adapted from those
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Runx also controls the proliferation and neuronal differenti
2018-11-12
Runx1 also controls the proliferation and neuronal differentiation of certain neural progenitor cell populations. In embryonic olfactory bulb progenitor cells in vivo, as well as in cultures of either embryonic olfactory progenitor cells or embryonic cortical NSPCs, Runx1 increases cell proliferatio
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However it is likely that in addition to PU
2018-11-09
However, it is likely that, in addition to PU.1, other TFs participate in the initiation of the establishment of pre-existing enhancers and the activation of de novo enhancers. Thus, C/EBPα sites also were enriched for the RUNX motif, in line with the finding that during myelopoiesis Runx1 binds tra
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br Taking into account the relations let us calculate the
2018-11-09
Taking into account the relations (15)–(17), let us calculate the integrals contained in the solution Using the equalities (4), (15)–(18), we obtain the formulae for the components of the displacement vector and the stress tensor at the points of the boundary plane : It is easily seen from
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Using the measured approach curves we determined the force a
2018-11-09
Using the measured approach curves, we determined the force acting on the probe from the sample surface as the product of the cantilever spring constant k by the piezoscanner movement value dZ (this quantity is plotted on the abscissa in Fig. 2b). Next, we constructed the F(δ) dependences to find Yo
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br Traceability quality and labelling
2018-11-09
Traceability, quality and labelling: foundations and previous research Methodology To find the answers to the questions we have referred to different sources of information. We differentiate between two sources of information: sources of primary information and sources of secondary information
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One of the most important ways that Mo can
2018-11-09
One of the most important ways that Mo can be concentrated and fractionated from Cu is through the oxidation–reduction cycle during chemical weathering on the surface of the Earth. During weathering, molybdenum is readily oxidized to form water-soluble MoO42− in surface environments (Sun et al., 201
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br Introduction Speech is an inherently variable signal toke
2018-11-09
Introduction Speech is an inherently variable signal: tokens of identical phonemes and words are acoustically distinct. When acquiring their native language, infants have thus to detect the equivalence of these different tokens in spite of their variability. For instance, the acoustic properties
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br Contributions of Authors EP
2018-11-09
Contributions of Authors EP, NA, MK and SB conceived the study; EP, JS and MM performed the in vitro work; EP, NA and SB designed the treatment protocol and analyzed the data; AC performed the molecular work on patient samples; BR was in charge of the anatomopathological analysis of patient sampl
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br Disclosure statement br Acknowledgements The authors than
2018-11-09
Disclosure statement Acknowledgements The authors thank Australian Wool Innovation Ltd (AWI) for financial support for the project that yielded material discussed in this article. Introduction Scientific study of human sleep has been initiated by the discovery that sleep progresses through
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br Results The mean age for the ND group
2018-11-09
Results The mean age for the ND group was 72±5.32, and 78.5±5.61 for the D group; there was no statistical difference between them (p=0.696). The underlying disease, for which the patients were admitted to the hospital did not influence the difference in the results since admission diagnoses were
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AMG-517 br Acknowledgments This work was supported by
2018-11-09
Acknowledgments This work was supported by SENTAN, Japan Science and Technology Agency (JST). Part of the microfluidic channel fabrication was conducted at the AIST Nano-Processing Facility, supported by the “Nanotechnology Platform Program” of the Ministry of Education, Culture, Sports, Science
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Introducci n br Caracter sticas
2018-11-09
Introducción Características estructurales del sistema energético nacional El funcionamiento del sistema energético nacional se gestó desde las décadas de 1970 y 1980. En ese marco jurídico e institucional, correspondió al Estado, en exclusividad, el manejo de las actividades centrales de los su
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