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br The world population faces various types of climate
2019-05-09

The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures
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protein kinase Although these studies demonstrated the effic
2019-05-09

Although these studies demonstrated the efficacy of pacemaker treatment for preventing or reducing VVS, all 3 trials were retrospective and uncontrolled [10]. Therefore, RCTs of cardiac pacing in VVS were proposed in the late 1990s. The era of RCTs: is pacemaker efficacy due to a placebo effect?
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br Methods As we were not privy to the
2019-05-09

Methods As we were not privy to the median year of enrolment, for all selected studies, the mean enrolment year ([start of enrolment+end of enrolment]/2) was calculated. If these dates were unavailable, the corresponding authors or sponsoring companies were contacted. When all methods to gather t
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br Materials and methods br Results
2019-05-09

Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential ha peptide (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation [1–4]. However
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Notwithstanding issues of equity improvement of research cap
2019-05-08

Notwithstanding issues of equity, improvement of research capacity in LMICs has practical benefits. People working and living in LMICs are better placed to define issues of importance to their populations than are people living thousands of miles away in HICs—who often fund research based on their o
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The data also revealed notable differences in
2019-05-08

The data also revealed notable differences in practice patterns across the countries. In France, Italy, Spain and the UK, patients were most likely to have multiple disseminated sites of metastases at the time of initial bone histone demethylase inhibitor detection; however, patients in Germany wer
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Pero m s all del folclore la conmemoraci n con
2019-05-08

Pero más allá del folclore, la conmemoración, con su ampulosidad y minucia, debía servir para medir la destreza virtuosa de los participantes, al exigir cierta competencia en la observancia de sus enigmas por parte de nuevos cristianos “ya bien enseñados en la Fe” (nos dice también Ávila) tras haber
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CaMKII phosphorylation of L type Ca
2019-05-08

CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 Tasquinimod and predisposing to early afterdepolarizations. Recently identified phosp
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Sultan et al retrospectively searched the
2019-05-08

Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop
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br Conflict of interest br Introduction Hepatosplenic T
2019-05-07

Conflict of interest Introduction Hepatosplenic T cell lymphoma (HSTCL) is a very rare type of hematologic malignancy, making up about 5% of peripheral T-cell lymphomas. It predominantly affects young male adults, with a higher incidence in patients submitted to immunosuppressive treatment for
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melanocortin receptor Delegates emphasised the urgent need f
2019-05-07

Delegates emphasised the urgent need for a consensus regarding the standards and guidelines among stakeholders in Kenya and Uganda. In addition, a common interpretation of the legal environment was considered crucial, and therefore the constitution and penal code would need to be harmonised in both
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br Community based bundled health interventions
2019-05-07

Community-based bundled health interventions are complex and challenging to implement, monitor, and assess in informal settlements (slums). Such settlements in urban areas are generally characterised by congestion, squalid conditions, deprivation, violence, crime, and poor sanitation. In Asia and
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HRU resulting from SREs is of
2019-05-07

HRU resulting from SREs is of increasing relevance in times of financial and economic restraint because it can help to determine the financial burden to hospital managers and payers. A separate analysis of the costs associated with SREs in this study found that the most costly SRE, spinal cord compr
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De esta forma siguiendo la multicitada met fora
2019-05-07

De esta forma, siguiendo la multicitada metáfora de Hemingway, el relato policiaco es solamente la punta del iceberg, mientras que los excesos de la política se encuentran debajo del mar (de lama). El relato policíaco, entonces, no es sólo un “pretexto narrativo”, o una simple guía para el lector me
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More than structural haemoglobin variants
2019-05-07

More than 900 structural haemoglobin variants have been described. Of these more than 100 show high oxygen affinity [2]. Erythrocytosis caused by Hb Ypsilanti was first described in 1967 [3], and the mutation results in substitution of amino buy diazoxide (β99 Asp→Tyr) involved in the stability of t
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