• In addition to CAF in the primary tumour microenvironment it

  2019-05-15

  

  In addition to CAF in the primary tumour microenvironment, it is tempting to speculate that fibroblasts within the bone itself may play a role in the establishment of metastatic deposits. Fibroblasts form a major component of the bone marrow stroma and regulate haematopoiesis by secreting a range of

• br Discussion To our knowledge we

  2019-05-14

  

  Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p

• In the APHRS survey most respondents answered

  2019-05-14

  

  In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate

• Nademanee et al reported nine symptomatic patients with BrS

  2019-05-14

  

  Nademanee et al. reported nine symptomatic patients with BrS who experienced VF and underwent electrophysiological study and catheter ablation [8]. The patients exhibited abnormal epicardial electrograms characterized by fragmented electrograms with a relatively low voltage ( Idiopathic ventricular

• A major development during was that OCV demand

  2019-05-13

  

  A major development during 2015 was that OCV demand exceeded supply (). The main reasons for this increase in demand are the observed feasibility of mass OCV campaigns and their ability to confer protection to underserved populations in complex situations. The increased availability and use of OCV h

• For most health care professionals infectious disease modell

  2019-05-13

  

  For most health-care professionals, infectious-disease modelling is something of a black box. One can see the input assumptions (ie, what goes in) and the outputs (ie, what comes out), but what happens in between seems close to magic. Given their complexity, to understand any one of the models used

• We also demonstrated by ELISA

  2019-05-13

  

  We also demonstrated by ELISA, ELISPOT and CTL assays the capacity of alum to induce a Th1 immune response. The evaluation of the Histone Acetyltransferases response against LALF32-51 peptide, E7 protein and LALF32-51-E7 fusion protein in immunized mice suggest that the antibodies response generated

• br To see how the quantity of osteosarcoma in

  2019-05-13

  

  To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma bethanechol chloride in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supplementary d

• br Material and methods br Results

  2019-05-13

  

  Material and methods Results Discussion The present study found that the plasma BNP level was higher in patients with LAA thrombus than in those without LAA thrombus. Additionally, the BNP level was negatively associated with peak LAA velocity evaluated using TEE and positively associated

• It is important to know whether pilsicainide can be used

  2019-05-13

  

  It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G

• Climate change will have far reaching effects on how we

  2019-05-13

  

  Climate change will have far-reaching effects on how we build, organise, and manage health systems as complex institutions. Yet, to date, these challenges have largely been ignored by the research community. Despite substantial work by WHO on the interface between climate and health, two major confe

• Si en La virgen de los sicarios la vida crapulosa

  2019-05-13

  

  Si en La virgen de los sicarios “la vida crapulosa está derrotando gsk-3 la muerte”, y “anda toda ventiada por Medellín día y noche en su afán haciendo lo que puede, compitiendo con semejante paridera, la más atroz [y] este continuo nacer de niños y el suero oral le están sacando canas”, para Ramíre

• Un segundo aspecto que deber a ser considerado para

  2019-05-13

  

  Un segundo aspecto que debería ser considerado para entender cabalmente por qué estas parentelas nobiliarias indígenas de Xolloco Acatla mostrarían una notable reluctancia (-)-p-Bromotetramisole Oxalate relacionarse con los poderes de San Pablo, y, por el contrario, habrían exhibido una interesada v

• br Procedural endpoints The most commonly employed electroph

  2019-05-13

  

  Procedural endpoints The most commonly employed electrophysiological endpoint is the achievement of noninducibility. While noninducibility has been shown to be predictive for clinical freedom from recurrent VT, it has not been uniformly the case [1,2]. Inducibility of VT is probabilistic and rare

• br Discussion In this case

  2019-05-13

  

  Discussion In this case report, we demonstrated the consistent fusion of P-waves during CS os pacing, except for the last captured beat, which was entrained but not fused, thereby satisfying the entrainment criteria [2,3]. The tachycardia could be induced with reproducible results by a single atr

15868 records 1020/1058 page Previous Next First page 上5页 10161017101810191020 下5页 Last page