• Welcome to the new volume of

  2019-05-09

  

  Welcome to the new volume of the , the official journal of the Japanese Heart Rhythm Society (JHRS) and the Asian Pacific Heart Rhythm Society (APHRS). The highlight of the 2013 volume is the publication of 2 . The first special issue is titled “Brugada syndrome from bench to bedside,” edited by gu

• The strengths of this definition are its simplicity and its

  2019-05-09

  

  The strengths of this definition are its simplicity and its usefulness in translating existing data into daily practice. The shortcomings of this definition include the lack of uniform criteria to suggest an impending fracture as well as the variable definitions of spinal cord leukotriene receptor a

• The goals of Vision the

  2019-05-09

  

  The goals of Vision 2020—the global initiative to eliminate avoidable blindness by 2020—include increasing cataract surgical rate and cataract surgical coverage. However, quality must not be sacrificed for quantity. The final visual outcome matters, both to the individual patient and to the communit

• Haemorrhagic stroke was once a major

  2019-05-09

  

  Haemorrhagic stroke was once a major cause of death in high-income nations, but its importance has receded in those regions over the 20th century. Our results suggest that, in the first decade of the 21st century, haemorrhagic stroke remains an important cause of death and disability worldwide. Wit

• br The world population faces various types of climate

  2019-05-09

  

  The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures

• protein kinase Although these studies demonstrated the effic

  2019-05-09

  

  Although these studies demonstrated the efficacy of pacemaker treatment for preventing or reducing VVS, all 3 trials were retrospective and uncontrolled [10]. Therefore, RCTs of cardiac pacing in VVS were proposed in the late 1990s. The era of RCTs: is pacemaker efficacy due to a placebo effect?

• br Methods As we were not privy to the

  2019-05-09

  

  Methods As we were not privy to the median year of enrolment, for all selected studies, the mean enrolment year ([start of enrolment+end of enrolment]/2) was calculated. If these dates were unavailable, the corresponding authors or sponsoring companies were contacted. When all methods to gather t

• br Materials and methods br Results

  2019-05-09

  

  Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential ha peptide (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation [1–4]. However

• Notwithstanding issues of equity improvement of research cap

  2019-05-08

  

  Notwithstanding issues of equity, improvement of research capacity in LMICs has practical benefits. People working and living in LMICs are better placed to define issues of importance to their populations than are people living thousands of miles away in HICs—who often fund research based on their o

• The data also revealed notable differences in

  2019-05-08

  

  The data also revealed notable differences in practice patterns across the countries. In France, Italy, Spain and the UK, patients were most likely to have multiple disseminated sites of metastases at the time of initial bone histone demethylase inhibitor detection; however, patients in Germany wer

• Pero m s all del folclore la conmemoraci n con

  2019-05-08

  

  Pero más allá del folclore, la conmemoración, con su ampulosidad y minucia, debía servir para medir la destreza virtuosa de los participantes, al exigir cierta competencia en la observancia de sus enigmas por parte de nuevos cristianos “ya bien enseñados en la Fe” (nos dice también Ávila) tras haber

• CaMKII phosphorylation of L type Ca

  2019-05-08

  

  CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 Tasquinimod and predisposing to early afterdepolarizations. Recently identified phosp

• Sultan et al retrospectively searched the

  2019-05-08

  

  Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop

• br Conflict of interest br Introduction Hepatosplenic T

  2019-05-07

  

  Conflict of interest Introduction Hepatosplenic T cell lymphoma (HSTCL) is a very rare type of hematologic malignancy, making up about 5% of peripheral T-cell lymphomas. It predominantly affects young male adults, with a higher incidence in patients submitted to immunosuppressive treatment for

• melanocortin receptor Delegates emphasised the urgent need f

  2019-05-07

  

  Delegates emphasised the urgent need for a consensus regarding the standards and guidelines among stakeholders in Kenya and Uganda. In addition, a common interpretation of the legal environment was considered crucial, and therefore the constitution and penal code would need to be harmonised in both

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