• Nuclear factor kappaB NF B as a

  2018-11-12

  

  Nuclear factor-kappaB (NF-κB), as a sensitive transcription factor for regulating the genes responsible for both innate and adaptive immune response, has been identified as a major factor involved in the regulation of pro-inflammatory cytokines such as iNOS and COX-2 [15]. Usually NF-κB resides in t

• There are many studies on antioxidant activity of A

  2018-11-12

  

  There are many studies on antioxidant activity of A. calamus for instance, the ethanolic extract prevented acrylamide-induced hind limb paralysis, decreased GSH and GST, increased dopamine receptors in the corpus striatum [37]. Ethyl acetate and methanolic extracts (50mg/kg bw) of A. calamus was eff

• Bystander effect between HSVtk positive cells and HSVtk nega

  2018-11-12

  

  Bystander effect between HSVtk-positive cells and HSVtk-negative cells has been extensively studied especially from the aspect of cell-to-cell communication. Connexin43, a major molecule in the connexin family gene products, has been reported to be related to the bystander effect in suicide gene the

• br Conclusions The results of this study are significant for

  2018-11-12

  

  Conclusions The results of this study are significant for a deeper understanding of the cellular changes that take place during ex vivo expansion of BMSCs and ASCs, and appear to concur with current knowledge on the use of hypoxic environments and the occurrence of replicative senescence. Relevan

• Concomitant with its suppressive effect

  2018-11-12

  

  Concomitant with its suppressive effect on blast colony formation, the inclusion of WNT3A, or the WNT agonist BIO, in methylcellulose cultures promoted the emergence of colonies we termed “mesospheres” (Figure 7H). These colonies were capable of osteogenic, adipogenic, and smooth muscle differentiat

• Due to the limited numbers of PGCs

  2018-11-12

  

  Due to the limited numbers of PGCs in mouse embryos, it is difficult to dissect the molecular mechanisms of early germ cell development. Recently, using ESC in vitro differentiation models, a number of studies demonstrated that Dazl, Blimp1, Lin28, and possibly Rhox6/Psx1, participated in PGC format

• We next aimed to test the differentiation capabilities of

  2018-11-12

  

  We next aimed to test the differentiation capabilities of the EZ spheres. We found that at any passage for all cell lines regardless of cryopreservation, EZ spheres can be placed in specific neural induction media for terminal neuronal or glial cell differentiation using protocols adapted from those

• Runx also controls the proliferation and neuronal differenti

  2018-11-12

  

  Runx1 also controls the proliferation and neuronal differentiation of certain neural progenitor cell populations. In embryonic olfactory bulb progenitor cells in vivo, as well as in cultures of either embryonic olfactory progenitor cells or embryonic cortical NSPCs, Runx1 increases cell proliferatio

• However it is likely that in addition to PU

  2018-11-09

  

  However, it is likely that, in addition to PU.1, other TFs participate in the initiation of the establishment of pre-existing enhancers and the activation of de novo enhancers. Thus, C/EBPα sites also were enriched for the RUNX motif, in line with the finding that during myelopoiesis Runx1 binds tra

• br Taking into account the relations let us calculate the

  2018-11-09

  

  Taking into account the relations (15)–(17), let us calculate the integrals contained in the solution Using the equalities (4), (15)–(18), we obtain the formulae for the components of the displacement vector and the stress tensor at the points of the boundary plane : It is easily seen from

• Using the measured approach curves we determined the force a

  2018-11-09

  

  Using the measured approach curves, we determined the force acting on the probe from the sample surface as the product of the cantilever spring constant k by the piezoscanner movement value dZ (this quantity is plotted on the abscissa in Fig. 2b). Next, we constructed the F(δ) dependences to find Yo

• br Traceability quality and labelling

  2018-11-09

  

  Traceability, quality and labelling: foundations and previous research Methodology To find the answers to the questions we have referred to different sources of information. We differentiate between two sources of information: sources of primary information and sources of secondary information

• One of the most important ways that Mo can

  2018-11-09

  

  One of the most important ways that Mo can be concentrated and fractionated from Cu is through the oxidation–reduction cycle during chemical weathering on the surface of the Earth. During weathering, molybdenum is readily oxidized to form water-soluble MoO42− in surface environments (Sun et al., 201

• br Introduction Speech is an inherently variable signal toke

  2018-11-09

  

  Introduction Speech is an inherently variable signal: tokens of identical phonemes and words are acoustically distinct. When acquiring their native language, infants have thus to detect the equivalence of these different tokens in spite of their variability. For instance, the acoustic properties

• br Contributions of Authors EP

  2018-11-09

  

  Contributions of Authors EP, NA, MK and SB conceived the study; EP, JS and MM performed the in vitro work; EP, NA and SB designed the treatment protocol and analyzed the data; AC performed the molecular work on patient samples; BR was in charge of the anatomopathological analysis of patient sampl

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